The homozygous variant p.Gln1311* in exon 28 of VWF is associated with the development of alloantibodies in 3 unrelated patients with type 3 VWD.

• Authors: Fanny Lassalle, Christophe Zawadzki, Annie Harroche, Christine Biron-Andréani, Céline Falaise, Pierre Boisseau, Nicolas Duployez, Emmanuelle Jeanpierre, Antoine Rauch, Camille Paris, Sophie Susen, Jenny Goudemand
• Journal: Haemophilia : the official journal of the World Federation of Hemophilia (Haemophilia) Vol. 27 Issue 4 Pg. e491-e494 (Jul 2021) ISSN: 1365-2516 [Electronic] England
• PMID: 33403757 (Publication Type: Letter)

Chemical References

• Isoantibodies
• von Willebrand Factor

Topics

• Adolescent
• Child
• Exons (genetics)
• Female
• Humans
• Isoantibodies
• Male
• von Willebrand Disease, Type 3
• von Willebrand Diseases (genetics)
• von Willebrand Factor (genetics)