Abstract |
One hundred twenty-eight nonmalnourished male patients between 3 and 36 months of age were randomly assigned to receive one of four lactose-free dietary treatments to determine the effect of dietary therapy on the severity and nutritional outcome of diarrheal illness. Group 1 received a formula diet composed of casein, sucrose, dextrin with maltose ( Dextri-Maltose), and vegetable oil to provide 110 kcal/kg body weight/d (CSO-110). Group 2 received CSO to provide 55 kcal/kg/d (CSO-55) for 2 days and then CSO-110. Group 3 received only oral glucose- electrolyte solution (GES) for 2 days, CSO-55 for the next 2 days, and then CSO-110. Group 4 received the same diets as Group 3 except that only intravenous GES was used for the first 2 days. The GES maintenance solutions provided 24 to 30 kcal/kg/d. Therapeutic success rates were similar among dietary groups, ranging from 90% to 97%. Fecal excretion was initially lower in group 4 (P less than 0.05) but was similar initially among groups treated orally and among all four groups beginning on day 3. Net apparent absorption of nitrogen, fat, carbohydrate, and total energy; retention of nitrogen; and increments in body weight, arm circumference, and skin-fold thickness were positively related to the amounts of dietary energy consumed. Thus continued oral feeding with the CSO diets during the early phase of therapy yielded improved nutritional results.
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Authors | K H Brown, A S Gastañaduy, J M Saavedra, J Lembcke, D Rivas, A D Robertson, R Yolken, R B Sack |
Journal | The Journal of pediatrics
(J Pediatr)
Vol. 112
Issue 2
Pg. 191-200
(Feb 1988)
ISSN: 0022-3476 [Print] United States |
PMID | 3339500
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)
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Chemical References |
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Topics |
- Absorption
- Acute Disease
- Child, Preschool
- Diarrhea
(diet therapy, physiopathology)
- Evaluation Studies as Topic
- Fluid Therapy
- Food, Formulated
- Humans
- Infant
- Male
- Nitrogen
(pharmacokinetics)
- Nutritional Physiological Phenomena
- Nutritional Status
- Random Allocation
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