This study aimed to determine the effects of
selenium on the immune toxicity of subacute
arsenic poisoning in chickens. Two hundred 8-day-old broilers were randomly divided into 5 groups: the control group (0.1 mg/kg As + 0.2 mg/kg Se), the As group (3 mg/kg As + 0.2 mg/kg Se), As + Se group I (3 mg/kg As + 5 mg/kg Se), As + Se group II (3 mg/kg As + 10 mg/kg Se), and As + Se group III (3 mg/kg As + 15 mg/kg Se). The conclusions were drawn based on the following measurements: 3.0 mg/kg added to feed led to a decrease in the growth performance of the broilers, reduced the level and conversion rate of
ANAE, reduced the
blood protein content of the broilers but had no effect on the
albumin/
globulin ratio, and had an inhibitory effect on erythrocyte immunity.
Selenium-added of 5 and 10 mg/kg in daily feed leads to increased growth performance, increases the positive rate and conversion rate of
ANAE, increases the
hemoglobin content of broilers, and promotes erythrocyte immunity, which indicates that the
selenium-added reduces the toxic effects of
arsenic; 3.0 mg/kg
arsenic with 15 mg/kg
selenium had the most severe toxic effects. Fifteen milligrams per kilogram of
selenium added in daily feed increases the toxicity of
arsenic to broilers. The dose of 10 mg/kg
selenium showed the best inhibitory effect on subacute
arsenic poisoning in the broilers.