Abstract | BACKGROUND: OBJECTIVE: PATIENTS AND METHODS: This intrapatient comparative study was conducted on 30 adult patients with idiopathic palmar hyperhidrosis. The palms of the patients were divided into 2 groups. Group 1 was treated with intradermal injections of 50 units of BoNTA, whereas Group 2 was subjected to laser-assisted transcutaneous BoNTA delivery using fractional CO2 laser at different doses (25, 50, and 75 units). Each treatment modality was evaluated using the iodine starch test, hyperhidrosis disease severity scale, and gravimetric scoring. RESULTS: Delivery of 75 units of BoNTA to the dermis on the right-sided palms assisted by fractional CO2 laser was clinically equivalent to 50 units of injection on the left side. Pain intensity was significantly higher on the injected side than on the other side. CONCLUSION:
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Authors | Naglaa F Agamia, Nagat Sobhy, Amira Abd-Elraouf, Abeer Tawfik |
Journal | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
(Dermatol Surg)
Vol. 47
Issue 5
Pg. 678-683
(05 01 2021)
ISSN: 1524-4725 [Electronic] United States |
PMID | 33337732
(Publication Type: Clinical Trial, Comparative Study, Journal Article)
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Copyright | Copyright © 2020 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved. |
Chemical References |
- Neuromuscular Agents
- Botulinum Toxins, Type A
- onabotulinum toxin A
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Topics |
- Administration, Cutaneous
- Adult
- Botulinum Toxins, Type A
(administration & dosage)
- Drug Delivery Systems
- Female
- Hand
- Humans
- Hyperhidrosis
(drug therapy)
- Injections, Intradermal
(adverse effects)
- Lasers, Gas
(adverse effects)
- Male
- Neuromuscular Agents
(administration & dosage)
- Pain
(etiology)
- Severity of Illness Index
- Young Adult
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