[An immunoenzyme method of determining apoprotein B and its diagnostic value in ischemic heart disease].

Abstract

Enzyme immunoassays were used to measure blood apoprotein B (apo-B), a major protein component of low-density lipoproteins, in 96 patients with coronary disease due to coronary atherosclerosis, 21 patients with angiographically intact coronary arteries, and 130 apparently normal individuals (donors). The results of serum apo-B measurements were correlated to the presence or absence of atherosclerotic coronary arterial lesions, the spread of coronary atherosclerosis, as evidenced by selective coronarography, and patients' sex and age. The measurement of serum apo-B may be helpful in early diagnosis of coronary disease, being particularly valuable in males below 50 years of age.

• Authors: O Iu Anisimova, S N Preobrazhenskiĭ, A A Liakishev, D V Preobrazhenskiĭ, A N Samko
• Journal: Kardiologiia (Kardiologiia) Vol. 27 Issue 10 Pg. 39-43 (Oct 1987) ISSN: 0022-9040 [Print] Russia (Federation)
• Vernacular Title: Immunofermentnyĭ metod opredeleniia apoproteina B i ego diagnosticheskoe znachenie pri ishemicheskoĭ bolezni serdtsa.
• PMID: 3320453 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Apolipoproteins B
• Triglycerides
• Cholesterol

Topics

• Adult
• Age Factors
• Apolipoproteins B (blood)
• Cholesterol (blood)
• Coronary Disease (blood, diagnosis)
• Female
• Humans
• Immunoenzyme Techniques
• Male
• Middle Aged
• Reference Values
• Sex Factors
• Triglycerides (blood)