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A controlled trial of ambroxol in chronic bronchitis.

Abstract
Ambroxol is a mucolytic agent which is widely used in chronic bronchitis in Europe. We conducted a double-blind randomized controlled trial of ambroxol vs matched placebo in 90 patients with chronic bronchitis and difficulty clearing secretions. It was concluded that there was no advantage to taking ambroxol.
AuthorsG H Guyatt, M Townsend, F Kazim, M T Newhouse
JournalChest (Chest) Vol. 92 Issue 4 Pg. 618-20 (Oct 1987) ISSN: 0012-3692 [Print] United States
PMID3308343 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Chemical References
  • Expectorants
  • Ambroxol
  • Bromhexine
Topics
  • Ambroxol (therapeutic use)
  • Bromhexine (analogs & derivatives)
  • Bronchitis (drug therapy)
  • Clinical Trials as Topic
  • Double-Blind Method
  • Expectorants (therapeutic use)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Random Allocation
  • Respiratory Function Tests

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