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Antinuclear antibodies in Thai patients with connective tissue diseases.

AbstractA study of antinuclear antibodies (ANA) among Thai patients with various connective tissue diseases revealed that the prevalence of ANA was similar to that in other countries, but that the ANA patterns showed interesting contrasts in most diseases. Rather than the predominant homogeneous pattern seen elsewhere in systemic lupus erythematosus and rheumatoid arthritis, the speckled pattern was commonest among Thai patients with these two diseases (67.9% and 76.9% respectively). Patients with scleroderma exhibited a much lower percentage of the nucleolar pattern (17%) than reported elsewhere. The discrepancy between our findings and those from other studies may reflect differences in genetics, the environment or the severity of disease.
AuthorsS Panicheewa, O Verasertniyom, S Chitrabamrung, M Vanichapuntu, M Vatanasuk
JournalAsian Pacific journal of allergy and immunology / launched by the Allergy and Immunology Society of Thailand (Asian Pac J Allergy Immunol) Vol. 5 Issue 1 Pg. 47-52 (Jun 1987) ISSN: 0125-877X THAILAND
PMID3304322 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antibodies, Antinuclear
Topics
  • Antibodies, Antinuclear (analysis)
  • Arthritis, Rheumatoid (immunology)
  • Connective Tissue Diseases (immunology)
  • Cross-Sectional Studies
  • Fluorescent Antibody Technique
  • Histocytochemistry
  • Humans
  • Lupus Erythematosus, Systemic (immunology)
  • Scleroderma, Systemic (immunology)
  • Thailand