Abstract | OBJECTIVE: The aim of the present 6-months' follow-up study was to assess the influence of single versus multiple sessions of photodynamic therapy ( PDT) as adjunct to scaling and root planning (SRP) on periodontopathogenic bacteria in patients with periodontitis. METHODS: Forty-five patients with periodontitis were included. The patients were randomly divided into 3 groups. In groups 1 (n = 15), 2 (n = 15) and 3 (n = 15), the patients under went SRP with PDT at (a) baseline; (b) baseline and after 1-month; and (c) baseline and after 1- and 3-months. Peri-implant plaque index (PI), bleeding on probing (BOP), probing depth (PD), clinical attachment loss (CAL) and marginal bone loss (MBL) were measured at baseline and 6-months follow-up. Counts of Porphyromonas gingivalis, Treponema denticola, Prevotella intermedia, Fusobacterium nucleatum and Aggregatibacter Actinomycetemcomitans were determined before SRP and at 4- and 6-months follow-up. RESULTS: All patients had grade-B periodontitis. There was no statistically significant difference in age and gender in all groups. At- 6-months' follow-up, patients that underwent SRP once showed significantly higher counts of periodontopathogenic bacteria in the oral biofilm compared with patients that received photobiomodulation twice or three times (P < 0.05). There was no significant difference in the periodontal parameters and counts of gram-negative bacteria in patients that received photobiomodulation 2 or 3 times. CONCLUSION: At least 2 sessions of PDT following baseline SRP is essential to achieve a significant reduction in the counts of subgingival bacteria in periodontitis patients over a 6-month follow-up period.
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Authors | Muzaheed, Sadananda Acharya, Abdulrahim R Hakami, Khaled S Allemailem, Khalid Alqahtani, Abdulrahman Al Saffan, Fahad M Aldakheel, Darshan Devang Divakar |
Journal | Photodiagnosis and photodynamic therapy
(Photodiagnosis Photodyn Ther)
Vol. 32
Pg. 102035
(Dec 2020)
ISSN: 1873-1597 [Electronic] Netherlands |
PMID | 33011399
(Publication Type: Journal Article, Randomized Controlled Trial)
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Copyright | Copyright © 2020 Elsevier B.V. All rights reserved. |
Chemical References |
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Topics |
- Dental Scaling
- Follow-Up Studies
- Humans
- Periodontal Attachment Loss
(drug therapy)
- Periodontal Pocket
(drug therapy)
- Periodontitis
(drug therapy)
- Photochemotherapy
(methods)
- Photosensitizing Agents
(therapeutic use)
- Porphyromonas gingivalis
- Root Planing
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