A novel carbamide peroxide polymeric nanoparticle bleaching gel: Color change and hydrogen peroxide penetration inside the pulp cavity.

Abstract

OBJECTIVE:

This study evaluated the hydrogen peroxide (HP) penetration inside the pulp cavity and the color change of teeth submitted to the 15% carbamide peroxide (CP) nanoparticle bleaching gel at several application times.

MATERIALS AND METHODS:

Premolars were divided into nine groups (n = 6) according to 15% CP bleaching agents (nanoparticle and commercial) and to application times (15, 30, 45, and 60 minutes). A negative control was exposed to ultra-purified water. After a whitening procedure, the HP concentration (μg/mL) inside the pulp cavity was assessed via spectrophotometry. The color change (ΔE* and ΔE00*) was evaluated with a spectrophotometer. Data were analyzed via two-way ANOVA and Tukey (α = 0.05).

RESULTS:

A lower concentration of HP was detected for CP nanoparticle gel after 30 and 45 minutes of whitening procedure (P = .001). The bleaching groups promoted a higher color change (ΔE* and ΔE00*) regardless of the application time (P = .0001).

CONCLUSIONS:

The CP nanoparticle gel reduced HP inside the pulp cavity, and showed effective bleaching compared with CP commercial gel.

CLINICAL SIGNIFICANCE:

Using 15% carbamide peroxide nanoparticle bleaching gel decreased the HP penetration inside the pulp cavity and may decrease bleaching-induced tooth sensitivity in at-home bleaching.

• Authors: Michael W Favoreto, Mariniella P Madureira, Viviane Hass, Bianca M Maran, Sibelli O Parreiras, Christiane P F Borges, Alessandra Reis, Alessandro D Loguercio
• Journal: Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] (J Esthet Restor Dent) Vol. 33 Issue 2 Pg. 277-283 (03 2021) ISSN: 1708-8240 [Electronic] England
• PMID: 32949453 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © 2020 Wiley Periodicals LLC.

Chemical References

• Peroxides
• Tooth Bleaching Agents
• Carbamide Peroxide
• Urea
• Hydrogen Peroxide

Topics

• Carbamide Peroxide
• Color
• Hydrogen Peroxide
• Nanoparticles
• Peroxides
• Tooth Bleaching
• Tooth Bleaching Agents
• Urea