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Evaluation of preoperative diflunisal for postoperative pain following periodontal surgery.

Abstract
The effectiveness of diflunisal as a preoperative medication to reduce pain following periodontal surgery was evaluated. Fifty patients were divided into two groups in a double-blind random manner: Group one received preoperative difunisal and Group two received preoperative placebo. The preoperative diflunisal group reported significantly less discomfort (P less than 0.05) than the preoperative placebo group and used rescue medication significantly less often (P less than 0.01). Therapeutic doses of diflunisal, given presurgically, are significantly more effective than placebo in limiting postoperative pain associated with periodontal surgery.
AuthorsJ S Minutello, D H Newell, W J Thrash, G T Terezhalmy
JournalJournal of periodontology (J Periodontol) Vol. 59 Issue 6 Pg. 390-3 (Jun 1988) ISSN: 0022-3492 [Print] United States
PMID3292753 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Chemical References
  • Placebos
  • Salicylates
  • Diflunisal
Topics
  • Adolescent
  • Adult
  • Clinical Trials as Topic
  • Diflunisal (administration & dosage, therapeutic use)
  • Double-Blind Method
  • Humans
  • Middle Aged
  • Pain, Postoperative (prevention & control)
  • Periodontal Diseases (surgery)
  • Placebos
  • Premedication
  • Random Allocation
  • Salicylates (therapeutic use)

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