Outcomes of patients with subarachnoid haemorrhage admitted to Australian and New Zealand intensive care units following a cardiac arrest.

Abstract

OBJECTIVES:

To describe the characteristics and outcomes of adults with a subarachnoid haemorrhage (SAH) admitted to Australian and New Zealand intensive care units (ICUs) with a cardiac arrest in the preceding 24 hours.

DESIGN:

Retrospective cohort study.

SETTING:

Study data from 144 Australian and New Zealand ICUs were obtained from the Australian and New Zealand Intensive Care Society Centre for Outcome and Resource Evaluation Adult Patient Database.

PARTICIPANTS:

A total of 439 of 11 047 (3.9%) patients admitted to an ICU with a SAH had a documented cardiac arrest in the 24 hours preceding their ICU admission. The mean age of patients with SAH and a preceding cardiac arrest was 55.3 years (SD, 13.7) and 251 of 439 (57.2%) were female.

MAIN OUTCOME MEASURES:

The primary outcome of interest was in-hospital mortality. Key secondary outcomes were ICU mortality, ICU and hospital lengths of stay, the proportion of patients discharged home.

RESULTS:

SAH patients with a history of cardiac arrest preceding ICU admission had a higher mortality rate (81.5% v 23.3%; P < 0.0001) and a lower rate of discharge home (4.6% v 37.0%; P < 0.0001) compared with patients with SAH who did not have a cardiac arrest. Among patients with SAH who had a cardiac arrest and survived, 20 of 81 (24.7%) were discharged home. In SAH patients with cardiac arrest, having a GCS of 3, the Australian and New Zealand Risk of Death score, and being admitted to ICU for palliative care or organ donation were significant predictors of in-hospital death.

CONCLUSIONS:

Almost one in five SAH patients who had a documented cardiac arrest in the 24 hours preceding ICU admission to an Australian and New Zealand ICU survived to hospital discharge, with around a quarter of these survivors discharged home. The neurological outcomes of these patients are uncertain, and understanding the burden of disability in survivors is an important area for further research.

• Authors: Jonathan Heaney, Eldho Paul, David Pilcher, Caleb Lin, Andrew Udy, Paul J Young
• Journal: Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine (Crit Care Resusc) Vol. 22 Issue 3 Pg. 237-244 (Sep 2020) ISSN: 1441-2772 [Print] Netherlands
• PMID: 32900330 (Publication Type: Journal Article)

Topics

• Adult
• Australia (epidemiology)
• Databases, Factual
• Female
• Heart Arrest (mortality)
• Hospital Mortality
• Humans
• Intensive Care Units (statistics & numerical data)
• Length of Stay (statistics & numerical data)
• Male
• Middle Aged
• New Zealand (epidemiology)
• Retrospective Studies
• Subarachnoid Hemorrhage (mortality, therapy)