BACKGROUND
Retinal vasoproliferative
tumor (VPT) is a type of ocular vascular
tumor that commonly occurs idiopathically and can be associated with secondary ocular diseases.
Ocular albinism is an X-linked inherited disease and distinguished from
oculocutaneous albinism by less hair and skin involvement. CASE REPORT A 42-year-old man with
ocular albinism and moderate
myopia presented with a history of insidious decrease in vision in both eyes over a period of months. On examination, the horizontal
pendular nystagmus was present and diffuse iris transillumination defects were observed bilaterally. A fundus examination revealed a depigmented fundus with visible choroidal vessels, foveal hypoplasia, and a unilateral, elevated, vascular lesion in the superotemporal aspect of the
retinal periphery. Optical coherence tomography of the lesion confirmed the
retinal location and
fluorescein fundus angiography indicated its vascular nature. B-scan ultrasonography was performed to measure the dimensions of the lesion. CONCLUSIONS Rare
retinal VPT has been reported with systemic and ocular associations, but it has never been reported in the literature in association with
ocular albinism. Multiple treatment modalities have been described for the
tumor, but observation can be considered in the absence of secondary consequences of the VPT.
Retinal VPT should be included in the differential diagnosis of any
retinal vascular abnormalities in patients with
ocular albinism.