Abstract | BACKGROUND: Cerebral aspergillosis usually affects immunocompromised hosts and may rarely occur in immunocompetent individuals. Due to its angio-invasive nature, Aspergillus may cause various vascular complications, particularly mycotic aneurysms and infarcts. CASE PRESENTATION: A 22-year-old immunocompetent male with diagnosed case of sino-cerebral aspergillosis was taking voriconazole for two months. His headache worsened and repeat imaging showed an increase in the size of the lesion. The patient was managed with right frontal craniotomy and surgical debridement, and voriconazole was continued. After ten days of uneventful post-operative course, the patient developed left-sided hemispheric infarct. The patient is doing well at nine months' follow-up, and he is off voriconazole for three months after the follow-up imaging showed complete resolution of disease. CONCLUSION:
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Authors | Nishant Goyal, Himanshu Narula, Jitender Chaturvedi, Sanjay Agrawal, Chinmaya Dash, Suneeta Meena, Neelam Kaistha |
Journal | Medical mycology journal
(Med Mycol J)
Vol. 61
Issue 3
Pg. 49-53
( 2020)
ISSN: 1882-0476 [Electronic] Japan |
PMID | 32863328
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Adult
- Aspergillosis
(complications, therapy)
- Aspergillus
(pathogenicity)
- Central Nervous System Fungal Infections
(complications, therapy)
- Cerebral Infarction
(etiology)
- Craniotomy
- Debridement
- Follow-Up Studies
- Humans
- Immunocompetence
- Male
- Voriconazole
(administration & dosage)
- Young Adult
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