A double-crossover trial comparing the effects of topical carteolol and placebo on intraocular pressure.

Abstract

The effect of topical carteolol 2% on the intraocular pressures of 12 patients suspected of having glaucoma was measured in a double-crossover trial of six weeks' duration. Carteolol produced a significant reduction in intraocular pressure (p less than or equal to 0.001), when compared with placebo. This represented reductions of 11% and 14%, after one and two weeks of treatment.

• Authors: G R Duff, P A Graham
• Journal: The British journal of ophthalmology (Br J Ophthalmol) Vol. 72 Issue 1 Pg. 27-8 (Jan 1988) ISSN: 0007-1161 [Print] England
• PMID: 3277664 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Propanolamines
• Carteolol

Topics

• Administration, Topical
• Carteolol (administration & dosage, therapeutic use)
• Clinical Trials as Topic
• Double-Blind Method
• Female
• Humans
• Male
• Ocular Hypertension (drug therapy)
• Propanolamines (therapeutic use)
• Time Factors