A new syndrome: angiotensin-converting enzyme dysfunction syndrome: differential diagnosis and pathogenesis--case reports.

Abstract

The authors previously reported a new syndrome, angiotensin-converting enzyme dysfunction syndrome (ACEDS), which is clinically characterized by mild systemic hypertension, a hypokalemic alkalosis, and hyperreninism with a high concentration of angiotensin-I (ANG-I), a normal angiotensin-II (ANG-II) value, and a normal aldosterone level. In the present study, they investigated the diagnosis and differentiation of diseases concomitant with hyperreninism, such as ACEDS, Bartter's syndrome, familial periodic paralysis, and renovascular hypertension treated with captopril for two months, and discussed the pathogenesis of ACEDS.

• Authors: S Umeki, A Terao, T Sawayama
• Journal: Angiology (Angiology) Vol. 39 Issue 1 Pt 1 Pg. 58-67 (Jan 1988) ISSN: 0003-3197 [Print] United States
• PMID: 3277490 (Publication Type: Case Reports, Comparative Study, Journal Article)

Chemical References

• Angiotensin II
• Aldosterone
• Angiotensin I
• Renin
• Potassium

Topics

• Adolescent
• Adult
• Aldosterone (blood)
• Angiotensin I (blood)
• Angiotensin II (blood)
• Bartter Syndrome (blood, drug therapy)
• Humans
• Hyperaldosteronism (blood)
• Hypertension, Renovascular (blood)
• Male
• Middle Aged
• Paralyses, Familial Periodic (blood, drug therapy)
• Paralysis (blood, physiopathology, therapy)
• Periodicity
• Potassium (therapeutic use)
• Renin (blood)
• Syndrome