Solitary retinovitreal abscess as the initial manifestation of cryptococcosis.

Abstract

In a 63-year-old white man with a history of long-term use of systemic corticosteroids for polyarteritis nodosa, progressive clouding of vision in the right eye developed over a 2-month period. Cytologic analysis of a fine-needle aspiration biopsy of a solitary fluffy retinovitreal mass demonstrated Cryptococcus neoformans. Subsequent cerebrospinal fluid cultures were also positive for C. neoformans. Systemic antifungal therapy was given using amphotericin-B and 5-fluorocytosine. Proliferative vitreoretinopathy developed in the right eye within 8 months. Three small yellow retinal lesions, which later resolved, developed in the fellow eye.

• Authors: P W Hiss, J A Shields, J J Augsburger
• Journal: Ophthalmology (Ophthalmology) Vol. 95 Issue 2 Pg. 162-5 (Feb 1988) ISSN: 0161-6420 [Print] United States
• PMID: 3262846 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Abscess (etiology)
• Cryptococcosis
• Endophthalmitis (etiology)
• Eye Diseases (etiology)
• Humans
• Male
• Middle Aged
• Retinal Diseases (etiology)
• Vitreous Body