A randomised trial to compare the results of injection sclerotherapy with a bulk laxative alone in the treatment of bleeding haemorrhoids.

Abstract

In a prospective randomised trial, 43 patients with bleeding haemorrhoids were allocated to receive either a bulk laxative with injection of phenol (5%) in arachis oil (20 patients) (Group 1), or a bulk laxative alone (23 patients) (Group 2). Treatment was given by one author and patients were assessed "blind" by the other at 6 weeks, 3 months and finally at 6 months. At 6 weeks 12 (48%) in Group 1 and 12 (57%) in Group 2 were still bleeding (NS; chi 2 = 0.54). At 3 months 10 (40%) in group 1 and 6 (35%) in group 2 (NS; chi 2 = 0.10), and at 6 months 10 (43%) in group 1 and 7 (47%) in group 2 were still bleeding (NS; chi 2 = 0.04). No significant difference in bleeding at 6 months after either injection sclerotherapy with bulk laxative or bulk laxatives alone was found.

• Authors: A Senapati, R J Nicholls
• Journal: International journal of colorectal disease (Int J Colorectal Dis) Vol. 3 Issue 2 Pg. 124-6 (Jun 1988) ISSN: 0179-1958 [Print] Germany
• PMID: 3261766 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Cathartics
• Peanut Oil
• Phenols
• Plant Oils
• Sclerosing Solutions
• Phenol

Topics

• Adult
• Aged
• Cathartics (therapeutic use)
• Double-Blind Method
• Female
• Gastrointestinal Hemorrhage (therapy)
• Hemorrhoids (therapy)
• Humans
• Male
• Middle Aged
• Peanut Oil
• Phenol
• Phenols (administration & dosage)
• Plant Oils
• Prospective Studies
• Random Allocation
• Sclerosing Solutions (therapeutic use)