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Morphea-like skin lesions reported in the phase 3 Long-Term Odanacatib Fracture Trial (LOFT) in postmenopausal women with osteoporosis.

AuthorsKenneth G Saag, Tobias J de Villiers, Peter Alexandersen, Heidi Jacobe, Carrie Kovarik, Victoria P Werth, Albert Leung, Avani Desai-Merchant, Julie Mattaliano, Deborah Gurner
JournalJournal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 84 Issue 4 Pg. 1113-1119 (Apr 2021) ISSN: 1097-6787 [Electronic] United States
PMID32553680 (Publication Type: Clinical Trial, Phase III, Journal Article, Randomized Controlled Trial)
Chemical References
  • Biphenyl Compounds
  • Bone Density Conservation Agents
  • Cathepsin K
  • odanacatib
Topics
  • Aged
  • Biphenyl Compounds (adverse effects)
  • Bone Density Conservation Agents (adverse effects)
  • Cathepsin K (antagonists & inhibitors)
  • Female
  • Humans
  • Osteoporosis, Postmenopausal (drug therapy)
  • Scleroderma, Localized (chemically induced)
  • Scleroderma, Systemic (chemically induced)

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