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Effects of kassinin, a tachykinin of the skin of the African frog Kassina senegalensis, on body fluid homeostasis in rats.

Abstract
In Wistar rats loaded with SC hypertonic NaCl solution kassinin produces an inhibition of cell-dehydration drinking which lasts several hours. The long duration of the effect does not depend on a renal excretion of sodium but, hypothetically, on a redistribution of electrolytes between the extra- and the intra-cellular compartments of body fluids.
AuthorsM Perfumi, G de Caro, I Panocka, C Polidori, M Massi
JournalPharmacological research communications (Pharmacol Res Commun) Vol. 20 Suppl 5 Pg. 67-70 (Dec 1988) ISSN: 0031-6989 [Print] United States
PMID3247356 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Kassinin
  • Sodium
Topics
  • Animals
  • Anura
  • Body Fluids (drug effects)
  • Diuresis (drug effects)
  • Drinking (drug effects)
  • Eating (drug effects)
  • Exploratory Behavior (drug effects)
  • Homeostasis (drug effects)
  • Injections, Intraventricular
  • Kassinin (administration & dosage, pharmacology)
  • Male
  • Motor Activity (drug effects)
  • Nephrectomy
  • Rats
  • Rats, Inbred Strains
  • Sodium (metabolism)

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