Abstract |
In Wistar rats loaded with SC hypertonic NaCl solution kassinin produces an inhibition of cell- dehydration drinking which lasts several hours. The long duration of the effect does not depend on a renal excretion of sodium but, hypothetically, on a redistribution of electrolytes between the extra- and the intra-cellular compartments of body fluids.
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Authors | M Perfumi, G de Caro, I Panocka, C Polidori, M Massi |
Journal | Pharmacological research communications
(Pharmacol Res Commun)
Vol. 20 Suppl 5
Pg. 67-70
(Dec 1988)
ISSN: 0031-6989 [Print] United States |
PMID | 3247356
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Animals
- Anura
- Body Fluids
(drug effects)
- Diuresis
(drug effects)
- Drinking
(drug effects)
- Eating
(drug effects)
- Exploratory Behavior
(drug effects)
- Homeostasis
(drug effects)
- Injections, Intraventricular
- Kassinin
(administration & dosage, pharmacology)
- Male
- Motor Activity
(drug effects)
- Nephrectomy
- Rats
- Rats, Inbred Strains
- Sodium
(metabolism)
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