Abstract |
A prolonged self-maintenance of haemopoietic tissue cells with stable chromosome rearrangements following a single intake of tritium oxide in the amount of 24 MBq/g of body weight (absorbed dose of 11 Gy) is shown. Mutant cells revealed long after the radionuclide exposure are descendants of stem-cell precursors, bearing stable chromosome aberrations during the period of formation of radiation injury after the radionuclide administration.
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Authors | K N Muksinova, N G Nikolaevskaia, T I Uriadnitskaia |
Journal | TSitologiia i genetika
(Tsitol Genet)
1988 Nov-Dec
Vol. 22
Issue 6
Pg. 39-42
ISSN: 0564-3783 [Print] Ukraine |
Vernacular Title | Chastota aberratsiĭ khromosom kletok kostnogo mozga krys v otdalennom periode posle odnokratnogo postupleniia tritiia. |
PMID | 3232204
(Publication Type: Comparative Study, English Abstract, Journal Article)
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Chemical References |
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Topics |
- Animals
- Bone Marrow
(radiation effects, ultrastructure)
- Cells, Cultured
- Chromosome Aberrations
- Hematopoietic Stem Cells
(radiation effects, ultrastructure)
- Male
- Metaphase
(radiation effects)
- Mutation
- Rats
- Rats, Inbred Strains
- Time Factors
- Tritium
(pharmacology)
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