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[The frequency of chromosome aberrations in rat bone marrow cells in the late period after a single uptake of tritium].

Abstract
A prolonged self-maintenance of haemopoietic tissue cells with stable chromosome rearrangements following a single intake of tritium oxide in the amount of 24 MBq/g of body weight (absorbed dose of 11 Gy) is shown. Mutant cells revealed long after the radionuclide exposure are descendants of stem-cell precursors, bearing stable chromosome aberrations during the period of formation of radiation injury after the radionuclide administration.
AuthorsK N Muksinova, N G Nikolaevskaia, T I Uriadnitskaia
JournalTSitologiia i genetika (Tsitol Genet) 1988 Nov-Dec Vol. 22 Issue 6 Pg. 39-42 ISSN: 0564-3783 [Print] Ukraine
Vernacular TitleChastota aberratsiĭ khromosom kletok kostnogo mozga krys v otdalennom periode posle odnokratnogo postupleniia tritiia.
PMID3232204 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Tritium
Topics
  • Animals
  • Bone Marrow (radiation effects, ultrastructure)
  • Cells, Cultured
  • Chromosome Aberrations
  • Hematopoietic Stem Cells (radiation effects, ultrastructure)
  • Male
  • Metaphase (radiation effects)
  • Mutation
  • Rats
  • Rats, Inbred Strains
  • Time Factors
  • Tritium (pharmacology)

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