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Shwachman-Bodian-Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia.

AuthorsMatthew D Dun, Abdul Mannan, Callum J Rigby, Stephen Butler, Hamish D Toop, Dominik Beck, Patrick Connerty, Jonathan Sillar, Richard G S Kahl, Ryan J Duchatel, Zacary Germon, Sam Faulkner, Mengna Chi, David Skerrett-Byrne, Heather C Murray, Hayley Flanagan, Juhura G Almazi, Hubert Hondermarck, Brett Nixon, Geoff De Iuliis, Janis Chamberlain, Frank Alvaro, Charles E de Bock, Jonathan C Morris, Anoop K Enjeti, Nicole M Verrills
JournalLeukemia (Leukemia) Vol. 34 Issue 12 Pg. 3393-3397 (12 2020) ISSN: 1476-5551 [Electronic] England
PMID32269318 (Publication Type: Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • Proteins
  • SBDS protein, human
  • Protein Phosphatase 2
Topics
  • Apoptosis (physiology)
  • Bone Marrow Diseases (metabolism)
  • Humans
  • Leukemia, Myeloid, Acute (metabolism)
  • Protein Phosphatase 2 (metabolism)
  • Proteins (metabolism)
  • Shwachman-Diamond Syndrome (metabolism)
  • Signal Transduction (physiology)

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