Late onset isofenphos neurotoxicity.

Abstract

Late progressive polyneuropathy followed by pyramidal findings in a 20 year old agricultural labourer who ingested Isofenphos solution during his work, is presented. The patient was confined to a wheelchair within 6 weeks, regained walking ability within 6 months, and a 23 months' follow up revealed slight additional clinical improvement with minimal progression of the pyramidal signs. The neuropathic clinical manifestations, the EMG and the nerve conduction studies were compatible with a pathology of a distal, mainly axonal, mainly motor neuropathy.

• Authors: A Catz, B Chen, I Jutrin, L Mendelson
• Journal: Journal of neurology, neurosurgery, and psychiatry (J Neurol Neurosurg Psychiatry) Vol. 51 Issue 10 Pg. 1338-40 (Oct 1988) ISSN: 0022-3050 [Print] England
• PMID: 3225590 (Publication Type: Case Reports, Journal Article)

Chemical References

• Insecticides
• Organothiophosphorus Compounds
• isofenphos

Topics

• Adult
• Electromyography
• Follow-Up Studies
• Humans
• Insecticides (poisoning)
• Male
• Motor Neurons (drug effects)
• Neuromuscular Diseases (chemically induced)
• Occupational Diseases (chemically induced)
• Organothiophosphorus Compounds (poisoning)
• Paralysis (chemically induced)