Analysis of lung air from patients with bronchogenic carcinoma and controls using gas chromatography-mass spectrometry.

Abstract

Volatile metabolites present in expired lung air were collected by odor sampling techniques and analyzed by gas chromatography-mass spectrometry. The study population included controls matched for age and smoking history with patients newly diagnosed with lung carcinoma. Significantly greater concentrations of o-toluidine were found in the lung air of patients with lung carcinoma than either age-matched or younger controls. Aniline was present in half of the patient population but absent in age-matched controls.

• Authors: G Preti, J N Labows, J G Kostelc, S Aldinger, R Daniele
• Journal: Journal of chromatography (J Chromatogr) Vol. 432 Pg. 1-11 (Nov 18 1988) Netherlands
• PMID: 3220881 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Aniline Compounds
• Tolonium Chloride

Topics

• Adult
• Aged
• Aging (metabolism)
• Air (analysis)
• Aniline Compounds
• Carcinoma, Bronchogenic (analysis)
• Female
• Gas Chromatography-Mass Spectrometry
• Humans
• Lung (analysis)
• Lung Neoplasms (analysis)
• Male
• Middle Aged
• Tolonium Chloride