[Peri-operative management of a pregnant patient with hereditary angioedema submitted to a cesarean-section: case report].

Abstract

Hereditary angioedema is an autosomal dominant disorder, presenting as sudden and recurring episodes of variable severity of subcutaneous and mucosa edema that may occur spontaneously or in response to triggers. There are three knwon types of hereditary angioedema. The disorder is caused by decrease in the plasma level or change in the functional capacity of C1 inhibitor, with increase in bradykinin and in vascular permeability, and consequent edema. Several measures are required in the perioperative period in order to avoid an acute attack. Prophylaxis should be carried out throughout pregnancy before any surgical procedure, before dental procedures, upon airway handling, on patients with previous episodes of angioedema, and when there are significant changes in volemia. The literature is scarce in regard to the association between hereditary angioedema and pregnancy. We describe a successful case of a pregnant patient with type I hereditary angioedema submitted to a C-section.

• Authors: Teresa Maria Ramos Nunes Estevens, Angel Serrano, Solange Amaro, João Ribeiro
• Journal: Brazilian journal of anesthesiology (Elsevier) (Braz J Anesthesiol) 2020 Jan - Feb Vol. 70 Issue 1 Pg. 48-50 ISSN: 2352-2291 [Electronic] Brazil
• Vernacular Title: Abordagem perioperatória de grávida com angioedema hereditário submetida a cesariana: relato de caso.
• PMID: 32178893 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2020 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.

Topics

• Adult
• Angioedemas, Hereditary (therapy)
• Cesarean Section
• Female
• Humans
• Perioperative Care
• Pregnancy
• Pregnancy Complications, Cardiovascular (therapy)