Abstract | BACKGROUND:
Allergic contact dermatitis to rubber accelerators in gloves has been well described in the literature. In response to this, glove manufacturers have recently marketed "accelerator-free" gloves. Little research has been done, to confirm whether these gloves are truly free from the accelerators known to cause contact dermatitis. OBJECTIVE: The aim of the study was to verify use of accelerators in reportedly accelerator-free/low- dermatitis-potential gloves. METHODS: A total of 16 commercially available medical gloves touted as "accelerator-free," "sensitive," or "low dermatitis potential" were obtained and analyzed via mass spectrometry (liquid chromatography heated electrospray ionization tandem mass spectrometry and liquid chromatography heated electrospray high-resolution tandem mass spectrometry) to determine whether any of the 9 known rubber accelerators were present (thiurams, carbamates, mercaptobenzothiazole, and diphenylguanidine). RESULTS: Despite marketing claims to the contrary, all tested gloves had at least 1 accelerant detected. Dipentamethylenethiuram disulfide, a thiuram, was found in all 16 gloves. Half of the gloves (8/16) contained more than 1 accelerator, with 1 glove having 5 rubber accelerators present. CONCLUSION: Patients with allergic contact dermatitis to accelerators should be aware potentially sensitizing accelerators may be present in gloves that are reported to not contain them.
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Authors | Makenzie E Pillsbury, Sanna Ronkainen, Molly Goodier, Sara A Hylwa |
Journal | Dermatitis : contact, atopic, occupational, drug
(Dermatitis)
2020 Mar/Apr
Vol. 31
Issue 2
Pg. 128-133
ISSN: 2162-5220 [Electronic] United States |
PMID | 32168144
(Publication Type: Journal Article, Retracted Publication)
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