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A phase 1/2 study of ruxolitinib and decitabine in patients with post-myeloproliferative neoplasm acute myeloid leukemia.

AuthorsPrithviraj Bose, Srdan Verstovsek, Jorge E Cortes, Susan Tse, Yvonne Gasior, Nitin Jain, Elias J Jabbour, Zeev Estrov, Yesid Alvarado, Courtney D DiNardo, Naveen Pemmaraju, Steven M Kornblau, Tapan M Kadia, Naval G Daver, Kiran Naqvi, Nicholas J Short, Lucia Masarova, John Villareal, Sherry A Pierce, Graciela Nogueras-Gonzalez, Xuelin Huang, Guillermo Garcia-Manero, Hagop M Kantarjian, Farhad Ravandi
JournalLeukemia (Leukemia) Vol. 34 Issue 9 Pg. 2489-2492 (09 2020) ISSN: 1476-5551 [Electronic] England
PMID32099037 (Publication Type: Clinical Trial, Phase I, Clinical Trial, Phase II, Letter, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
Chemical References
  • Nitriles
  • Pyrazoles
  • Pyrimidines
  • Decitabine
  • ruxolitinib
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Decitabine (administration & dosage)
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Leukemia, Myeloid, Acute (drug therapy)
  • Male
  • Middle Aged
  • Myeloproliferative Disorders (pathology)
  • Neoplasms, Second Primary (drug therapy)
  • Nitriles
  • Pyrazoles (administration & dosage)
  • Pyrimidines
  • Treatment Outcome

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