Drugs, including alcohol, that act as risk factors for cataract, and possible protection against cataract by aspirin-like analgesics and cyclopenthiazide.

Abstract

A case-control study of cataract in Oxfordshire explored the risks and benefits associated with a variety of drugs. Steroids including the diuretic spironolactone, nifedipine, heavy smoking, and beer drinking were associated with a raised risk. On the other hand aspirin-like analgesics (paracetamol, ibuprofen, aspirin, etc. appeared to protect against cataract. Cyclopenthiazide appeared to provide a similar protection.

• Authors: J J Harding, R van Heyningen
• Journal: The British journal of ophthalmology (Br J Ophthalmol) Vol. 72 Issue 11 Pg. 809-14 (Nov 1988) ISSN: 0007-1161 [Print] England
• PMID: 3207655 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Diuretics
• Sodium Chloride Symporter Inhibitors
• Steroids
• Nifedipine
• Cyclopenthiazide

Topics

• Aged
• Alcohol Drinking
• Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
• Cataract (chemically induced, etiology, prevention & control)
• Cyclopenthiazide (therapeutic use)
• Diuretics (adverse effects)
• Drug-Related Side Effects and Adverse Reactions
• Female
• Humans
• Male
• Middle Aged
• Nifedipine (adverse effects)
• Risk Factors
• Smoking (adverse effects)
• Sodium Chloride Symporter Inhibitors (therapeutic use)
• Steroids (adverse effects)