[Annual rhythm of the excretion of indole melanogen in human urine].

Abstract

Comparing the monthly indole melanogen mean values (4,100 single values within 5 years) in patients with malignant melanomas showing a normal urinary indole melanogen concentration we have found a seasonal effect with a maximum melanogen excretion in spring (March) and summer (July) and a minimum in autumn (September). These results are statistically significant. The possible importance of these seasonal influences for the prognosis in individual cases of malignant melanoma is discussed.

• Authors: G Schwartze
• Journal: Archiv fur Geschwulstforschung (Arch Geschwulstforsch) Vol. 58 Issue 5 Pg. 341-4 ( 1988) ISSN: 0003-911X [Print] Germany
• Vernacular Title: Jahresrhythmik der Ausscheidung von Indolmelanogenen im menschlichen Harn.
• PMID: 3202684 (Publication Type: English Abstract, Journal Article)

Chemical References

• Indoles
• melanogen

Topics

• Humans
• Indoles (urine)
• Melanoma (urine)
• Periodicity