Treatment for AIDS and other retrovirus-caused diseases.

Abstract

The role of retroviruses as causal agents in animal and human neoplasms is reviewed. Based on previous studies done on retrovirus caused mouse mammary adenocarcinoma, it is suggested that a treatment regimen with 6-propylthiouracil, chloroquine phosphate and 5-fluorouracil (which resulted in 77% and 65% complete mouse tumor remission), may be effective in treating AIDS and other retrovirus-caused diseases.

• Authors: J P Shoemaker
• Journal: Medical hypotheses (Med Hypotheses) Vol. 27 Issue 2 Pg. 147-8 (Oct 1988) ISSN: 0306-9877 [Print] United States
• PMID: 3200174 (Publication Type: Journal Article)

Chemical References

• chloroquine diphosphate
• Propylthiouracil
• Chloroquine
• Fluorouracil

Topics

• Acquired Immunodeficiency Syndrome (drug therapy)
• Animals
• Chloroquine (analogs & derivatives, therapeutic use)
• Drug Therapy, Combination
• Fluorouracil (therapeutic use)
• Humans
• Mice
• Propylthiouracil (therapeutic use)