Long-term Outcome of Zonal Outer Retinopathy in Punctate Inner Choroidopathy or Multifocal Choroiditis.

Abstract

Purpose: To report the long-term prognosis of punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC) and associated zonal outer retinopathy (ZOR).Method: Retrospective study in patients with PIC/MFC and ZOR with a clinical follow-up of 4 years or longer.Results: There were 14 patients in this study (M: F = 11:3). All patients received systemic steroid therapy. The initial and final median logarithm of minimal angle of resolution of BCVA were 1.00 and 0.22 (p = .002). Ellipsoid zone recovery was noted in all patients. The median visual field loss improved from -6.38 dB to -3.41 dB (p = .035). The median of total area of PIC/MFC lesions enlarged from 6.82 mm2 to 8.77 mm2 (p = .005). Recurrent disease was noted in 4 eyes and maintenance steroid was needed in 3 eyes.Conclusion: With steroid therapy, most patients with PIC/MFC and ZOR had good visual prognosis.

• Authors: San-Ni Chen, Yi-Ling Chen, Benjamin Chi-Lan Yang
• Journal: Ocular immunology and inflammation (Ocul Immunol Inflamm) Vol. 29 Issue 5 Pg. 865-870 (Jul 04 2021) ISSN: 1744-5078 [Electronic] England
• PMID: 31906767 (Publication Type: Journal Article)

Chemical References

• Coloring Agents
• Glucocorticoids
• Indocyanine Green
• Methylprednisolone

Topics

• Adult
• Coloring Agents (administration & dosage)
• Computed Tomography Angiography
• Female
• Fluorescein Angiography
• Follow-Up Studies
• Glucocorticoids (therapeutic use)
• Humans
• Indocyanine Green (administration & dosage)
• Male
• Methylprednisolone (therapeutic use)
• Multifocal Choroiditis (diagnosis, drug therapy, physiopathology)
• Retrospective Studies
• Scotoma (diagnosis, drug therapy, physiopathology)
• Tomography, Optical Coherence
• Treatment Outcome
• Visual Acuity (physiology)
• Visual Fields (physiology)
• White Dot Syndromes (diagnosis, drug therapy, physiopathology)
• Young Adult