Abstract |
The screening of the preparations of blood plasma obtained from 1,608 donors made it possible to establish the presence of high titers of natural antibodies to Re-glycolipid in 3% of the donors. Donor plasma containing antibodies to Re-glycolipid in a titer of 1:128 ensured a high level of protection for mice in experimental fecal peritonitis. The treatment of 10 patients having commonly occurring forms of peritonitis, caused by Gram-negative bacteria, with the use of such plasma yielded a positive clinical effect. The presence of correlation between the titers of antibodies to Re-glycolipid in blood plasma preparations and the content of high-density lipoproteids, expressed in per cent, was noted.
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Authors | A A Rudik, E I Kropacheva, A V Apollonin, E K Sevast'ianova, V G Likhoded |
Journal | Zhurnal mikrobiologii, epidemiologii i immunobiologii
(Zh Mikrobiol Epidemiol Immunobiol)
Issue 7
Pg. 60-3
(Jul 1988)
ISSN: 0372-9311 [Print] Russia (Federation) |
Vernacular Title | Protektivnaia aktivnost' preparatov plazmy krovi donorov s vysokim titrom estestvennykh antitel k Re-glikolipidu gramotritsatel'nykh bakteriĭ. |
PMID | 3188736
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Antibodies
- Glycolipids
- Re-glycolipid
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Topics |
- Adolescent
- Adult
- Animals
- Antibodies
(isolation & purification)
- Blood Donors
- Female
- Glycolipids
(immunology)
- Gram-Negative Bacteria
(pathogenicity)
- Humans
- Male
- Mice
- Middle Aged
- Plasma
(immunology)
- Virulence
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