[Influence of the oral administration of indigenous microorganisms on the resistance of mice to Salmonella infection].

Abstract

The influence of the oral administration of killed bifidobacteria, lactobacteria, bacteroids and fusobacteria on the anti- Salmonella resistance of mice, infected orally with S. dublin, was studied. Bifidobacteria and lactobacteria were shown to produce a dose-dependent immunostimulating effect. The oral administration of killed bifidobacteria and lactobacteria led to the enhanced resistance of mice to Salmonella infection. The oral administration of killed bifidobacteria was conductive to the normalization of the intestinal microflora in dysbacteriosis developing in cases of Salmonella infection. Bacteroids and fusobacteria were found to possess no such effect.

• Authors: M M Shkarupeta, V M Korshunov, V T Savenkova, B V Pinegin
• Journal: Zhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) Issue 7 Pg. 46-50 (Jul 1988) ISSN: 0372-9311 [Print] Russia (Federation)
• Vernacular Title: Vliianie peroral'nogo vvedeniia indigennykh mikroorganizmov na ustoĭchivost' mysheĭ k sal'monelleznoĭ infektsii.
• PMID: 3188735 (Publication Type: English Abstract, Journal Article)

Chemical References

• Bacterial Vaccines
• Vaccines, Inactivated

Topics

• Administration, Oral
• Animals
• Bacterial Vaccines (administration & dosage)
• Bacteroides fragilis (immunology)
• Bifidobacterium (immunology)
• Fusobacterium (immunology)
• Lactobacillus (immunology)
• Mice
• Salmonella Infections, Animal (immunology)
• Vaccines, Inactivated (administration & dosage)