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Black Bone Disease of the Skull.

Abstract
We present an image of a patient's skull characterized by dark, irregular discoloration. This was discovered incidentally in a 66-year-old man who underwent craniotomy for resection of a glioblastoma. This image demonstrates cranial black bone disease. This is an abnormal bone pigmentation associated with long-term tetracycline use, as occurred in this patient.
AuthorsDavid E Smolar, Monica C Mureb, Robert A Fenstermaker
JournalWorld neurosurgery (World Neurosurg) Vol. 134 Pg. 548 (Feb 2020) ISSN: 1878-8769 [Electronic] United States
PMID31785440 (Publication Type: Case Reports)
CopyrightCopyright © 2019 Elsevier Inc. All rights reserved.
Chemical References
  • Anti-Bacterial Agents
  • Tetracycline
Topics
  • Aged
  • Anti-Bacterial Agents (pharmacology)
  • Bone Diseases (drug therapy, surgery)
  • Craniotomy (methods)
  • Glioblastoma (drug therapy)
  • Humans
  • Male
  • Skull (drug effects, surgery)
  • Tetracycline (pharmacology)
  • Time
  • Tomography, X-Ray Computed

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