Abstract | BACKGROUND:
Aneurysm of the main pulmonary artery trunk (PAA) is a rare but severe complicating factor in patients suffering from pulmonary arterial hypertension (PAH). Many centers consider PAA an indication for a heart-lung transplantation. We aimed to summarize our institutional experience with a lung-only strategy in this complex group of patients. METHODS: We performed a retrospective single-center analysis of patients with PAH and a severe PAA who underwent lung transplantation between January 1996 and November 2018. RESULTS: A total of 127 patients with PAH underwent lung transplantation during the study period. Seven patients presented with severe PAA (mean diameter, 70.4 mm). Donor lungs were procured together with the main pulmonary artery (PA). In the recipient, cardiopulmonary bypass with bicaval cannulation was established, and bilateral pneumonectomy together with resection of the entire PA trunk was performed. The right donor lung was implanted, and the attached PA trunk was pulled through behind the superior vena cava and ascending aorta. Anastomosis was performed just above the level of the pulmonary valve. Thereafter, the left lung was implanted by reconnecting the left PA to the main PA trunk. All but 1 patient, who died from sepsis on postoperative day 13, were successfully discharged. CONCLUSIONS:
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Authors | Stefan Schwarz, Alberto Benazzo, Helmut Prosch, Peter Jaksch, Walter Klepetko, Konrad Hoetzenecker, Vienna Lung Transplant Group |
Journal | The Journal of thoracic and cardiovascular surgery
(J Thorac Cardiovasc Surg)
Vol. 159
Issue 6
Pg. 2543-2550
(06 2020)
ISSN: 1097-685X [Electronic] United States |
PMID | 31780060
(Publication Type: Journal Article, Video-Audio Media)
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Copyright | Copyright © 2019 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved. |
Topics |
- Adult
- Aneurysm
(diagnostic imaging, etiology, physiopathology, surgery)
- Arterial Pressure
- Female
- Humans
- Lung Transplantation
(adverse effects)
- Male
- Middle Aged
- Pulmonary Arterial Hypertension
(complications, diagnostic imaging, physiopathology, surgery)
- Pulmonary Artery
(diagnostic imaging, physiopathology, transplantation)
- Retrospective Studies
- Time Factors
- Treatment Outcome
- Young Adult
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