Autoimmune pancreatitis: an update.

Abstract

OBJECTIVE:

Since the time of inception of autoimmune pancreatitis (AIP), our knowledge of autoimmune pancreatitis has expanded significantly. The aim of this review is to provide an update on clinical manifestations, diagnosis, imaging features, and treatment of AIP.

BACKGROUND AND CLINICAL SIGNIFICANCE:

Type 1 AIP is the pancreatic manifestation of IgG4-related systemic disease, which can be diagnosed using a combination of clinical, histopathological, pancreatic imaging findings in conjunction with manifestation in other organs, as well of responsiveness to steroid treatment. It is vital to differentiate AIP from pancreatic cancer since both can mimic each other clinically and radiologically. Type 2 AIP is a rare but distinct subtype of AIP which occurs mostly in the younger patient.

CONCLUSION:

AIP is steroid-responsive chronic pancreatitis with distinct manifestations on imaging.

• Authors: Ashish Khandelwal, Dai Inoue, Naoki Takahashi
• Journal: Abdominal radiology (New York) (Abdom Radiol (NY)) Vol. 45 Issue 5 Pg. 1359-1370 (05 2020) ISSN: 2366-0058 [Electronic] United States
• PMID: 31650376 (Publication Type: Journal Article, Review)

Chemical References

• Adrenal Cortex Hormones
• Biomarkers
• Immunoglobulin G

Topics

• Adrenal Cortex Hormones (therapeutic use)
• Autoimmune Pancreatitis (diagnostic imaging, drug therapy)
• Biomarkers (analysis)
• Humans
• Immunoglobulin G (immunology)
• Prognosis