Study of eosinophilia in relation to serum IgE level and cell mediated immunity (CMI) to soluble egg antigen (SEA) in human schistosomiasis mansoni.

Abstract

Eosinophil count, delayed intradermal test and lymphoblast transformation test (LTT) using SEA, have been used to study the correlation of eosinophilia with CMI in patients with schistosomiasis mansoni. Only a weak positive correlation was found between the eosinophil count and both in vivo and in vitro manifestations of CMI. When IgE serum level was correlated with eosinophil count, a positive correlation was only found in cases with hepato-splenic disease (those with increased CMI).

• Authors: S H Khalil, H Khalil Sr, M H Fahmy, M Said, M el Sawy, M Nofal, F Amara, M Taky, J Brock, M Arab
• Journal: Allergie und Immunologie (Allerg Immunol (Leipz)) Vol. 31 Issue 2 Pg. 105-8 ( 1985) ISSN: 0323-4398 [Print] Germany
• PMID: 3161309 (Publication Type: Journal Article)

Chemical References

• Antigens, Helminth
• Immunoglobulin E
• Ovalbumin

Topics

• Antigens, Helminth (immunology)
• Eosinophilia (etiology, immunology)
• Eosinophils
• Humans
• Immunity, Cellular
• Immunoglobulin E (analysis)
• Intradermal Tests
• Leukocyte Count
• Lymphocyte Activation
• Male
• Ovalbumin (immunology)
• Schistosoma mansoni (isolation & purification)
• Schistosomiasis (complications, immunology)