Prevalence and clinical peculiarities of essential hypertension in a population living at high altitude.

Abstract

Screening examinations were performed in ethnically related populations of men aged 30-59 years, living in high mountain regions of Tien-Shan and Pamir (2800-3600 m above sea level) and in the lowlands (800-900 m). The incidence of borderline hypertension (BH) and essential hypertension (EH) was statistically significantly higher among the inhabitants of lowland regions: EH was recorded among them in 15.4%, vs. 4.2% among men living at high altitude; BH was present among the male lowland population (LL) in 10.6% vs. 6.0% among highlanders (HL). The main characteristic clinico-functional feature of EH in HL was its frequent association with high-altitude pulmonary hypertension and right ventricular hypertrophy. Aldosterone excretion was in HL with EH substantially lower, and sodium excretion higher, than in a comparable group of lowland inhabitants.

• Authors: M M Mirrakhimov, Zh S Rafibekova, A S Dzhumagulova, T S Meimanaliev, T M Murataliev, K K Shatemirova
• Journal: Cor et vasa (Cor Vasa) Vol. 27 Issue 1 Pg. 23-8 ( 1985) ISSN: 0010-8650 [Print] Czech Republic
• PMID: 3158478 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Aldosterone
• Potassium

Topics

• Adult
• Age Factors
• Aldosterone (blood)
• Alkalosis, Respiratory (etiology, metabolism)
• Altitude
• Altitude Sickness (complications, epidemiology)
• Cardiomegaly (epidemiology, etiology)
• Humans
• Hypertension (epidemiology, metabolism)
• Hypertension, Pulmonary (epidemiology, etiology)
• Kyrgyzstan
• Lipid Metabolism
• Male
• Middle Aged
• Occupations
• Potassium (analysis)