Abstract | PURPOSE OF REVIEW: To summarize recent data on the role of dyslipidaemia and the benefit from managing this in people with disease of the abdominal aorta and its peripheral branches ( peripheral artery disease, PAD). RECENT FINDINGS: SUMMARY: Effective methods to educate physicians and patients on best medical management are needed. Further research is needed to examine the benefit of LDL-c lowering and other lipid therapies for PAD-specific problems like abdominal aortic aneurysm progression and walking impairment. Other novel lipid therapies, such as those that lower lipoprotein (a), maybe particularly beneficial to people with PAD given the evidence indicating high concentrations in this population and the high incidence of MACE in these individuals.
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Authors | Jonathan Golledge, Natalie C Ward, Gerald F Watts |
Journal | Current opinion in lipidology
(Curr Opin Lipidol)
Vol. 30
Issue 6
Pg. 470-476
(12 2019)
ISSN: 1473-6535 [Electronic] England |
PMID | 31577608
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
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Chemical References |
- Cholesterol, LDL
- PCSK9 protein, human
- Proprotein Convertase 9
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Topics |
- Animals
- Aortic Aneurysm, Abdominal
(blood, etiology, therapy)
- Cholesterol, LDL
(blood)
- Clinical Trials as Topic
- Humans
- Myocardial Infarction
(blood, etiology, therapy)
- Peripheral Arterial Disease
(blood, complications, therapy)
- Proprotein Convertase 9
(blood)
- Stroke
(blood, etiology, therapy)
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