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A novel form of GD1c ganglioside IV3 (NeuAc alpha 2-8 NeuGc)Gg4Cer from murine X-ray induced thymoma.

Abstract
Four disialoganglioside fractions were isolated from X-ray induced thymoma in C57Bl/6 mice. On the basis of compositional and methylation analyses as well as degradation with specific exoglycosidases a novel form of GD1c ganglioside NeuAc alpha 2-8 NeuGc alpha 2-3 Gal beta 1-3 GalNAc beta 1-4 Gal beta 1-4 GlcCer was identified.
AuthorsT Pacuszka, J Antoniewicz
JournalActa biochimica Polonica (Acta Biochim Pol) Vol. 35 Issue 4 Pg. 387-93 ( 1988) ISSN: 0001-527X [Print] Poland
PMID3150198 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Gangliosides
  • (N-acetylneuraminosyl-(2--8)-N-glycolylneuraminic acid)gangliotetraosylceramide
  • Glycoside Hydrolases
  • Neuraminidase
Topics
  • Animals
  • Chromatography, Thin Layer
  • Gangliosides (isolation & purification)
  • Glycoside Hydrolases (metabolism)
  • Methylation
  • Mice
  • Molecular Structure
  • Neoplasms, Radiation-Induced (analysis)
  • Neuraminidase (metabolism)
  • Thymoma (analysis, etiology)
  • Thymus Neoplasms (analysis, etiology)

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