Graphene quantum dots (GQDs)-based nanomaterials for improving photodynamic therapy in cancer treatment.

Abstract

Graphene quantum dots (GQDs) as novel nanomaterials, have received significant interest in the field of biomedical applications. It is worth noting that a large amount of research is devoted to GQDs-based nanocomposites for cancer treatment, especially for photodynamic therapy (PDT), in that they can act not only as more favorable photosensitizers (PSs) but also nanoplatforms for delivering PSs. In this review, the biological behavior and physicochemical properties of GQDs for PDT are described in detail, and the application of GQDs-based nanocomposites in improved PDT and PDT-based combination therapies is analyzed, which may provide a new strategy for designing efficient PDT systems for cancer treatment.

• Authors: Hua-Yang Fan, Xiang-Hua Yu, Ke Wang, Yi-Jia Yin, Ya-Jie Tang, Ya-Ling Tang, Xin-Hua Liang
• Journal: European journal of medicinal chemistry (Eur J Med Chem) Vol. 182 Pg. 111620 (Nov 15 2019) ISSN: 1768-3254 [Electronic] France
• PMID: 31470307 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2019 Elsevier Masson SAS. All rights reserved.

Chemical References

• Antineoplastic Agents
• Drug Carriers
• Photosensitizing Agents
• Graphite

Topics

• Antineoplastic Agents (chemistry, pharmacology)
• Drug Carriers (chemistry)
• Graphite (chemistry)
• Humans
• Nanoparticles (chemistry)
• Neoplasms (drug therapy)
• Photochemotherapy
• Photosensitizing Agents (chemistry, pharmacology)
• Quantum Dots (chemistry)
• Structure-Activity Relationship