[The significance of the antihypoxic properties of etimizol in its nootropic action].

Abstract

The antihypoxic effects of etimizol and other nootropics are analysed on various experimental models of hypoxia and during bicycle ergometric exercise in healthy volunteers. Etimizol was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain). The advantage of etimizol as compared to other nootropics with similar action (meclofenoxate, piracetam) is its high effectiveness at a single administration.

• Authors: Iu V Zaĭtsev, P D Shabanov, S I Bogoslovskaia, V A Krauz, Kh D Fisher
• Journal: Farmakologiia i toksikologiia (Farmakol Toksikol) 1988 Sep-Oct Vol. 51 Issue 5 Pg. 27-30 ISSN: 0014-8318 [Print] Russia (Federation)
• Vernacular Title: Znachenie antigipoksicheskikh svoĭstv étimizola v ego nootropnom deĭstvii.
• PMID: 3145213 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Imidazoles
• Psychotropic Drugs
• Meclofenoxate
• Etimizol
• Piracetam

Topics

• Amnesia (prevention & control)
• Animals
• Atmosphere Exposure Chambers
• Avoidance Learning (drug effects)
• Etimizol (pharmacology)
• Exercise Test
• Hemodynamics (drug effects)
• Humans
• Hypoxia (prevention & control)
• Imidazoles (pharmacology)
• Meclofenoxate (pharmacology)
• Piracetam (pharmacology)
• Psychotropic Drugs
• Rats