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Lipase deficiencies.

Abstract
Two enzymes, lipoprotein lipase and hepatic triglyceride lipase, are involved in the hydrolysis of triglycerides from chylomicrons and very low density lipoprotein (VLDL). Lipoprotein lipase has an absolute requirement for apolipoprotein CII for activity. Three inborn errors of metabolism which give rise to hypertriglyceridaemia have been described. The biochemical and clinical aspects of these disorders, lipoprotein lipase deficiency (familial type I hyperlipoproteinaemia), hepatic triglyceride lipase deficiency and apo-CII deficiency are discussed.
AuthorsH Greten, F U Beil
JournalJournal of inherited metabolic disease (J Inherit Metab Dis) Vol. 11 Suppl 1 Pg. 29-32 ( 1988) ISSN: 0141-8955 [Print] United States
PMID3141684 (Publication Type: Journal Article, Review)
Chemical References
  • Lipase
Topics
  • Humans
  • Lipase (deficiency)
  • Lipid Metabolism, Inborn Errors (enzymology, genetics)

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