Investigations on the early diagnosis of cystinuria in children.

Abstract

The procedure described confirms that the Ni2+/S2O4(2-) tablet test is a suitable quick cystine screening test for large groups. In 16 (0.67%) of 2,395 one- to three-year-old crèche children significantly enhanced cystine levels of 0.60-0.96 mmol/l were found. The corresponding creatinine values (mmol/l) did not reveal any significant deviations from the normal values. In a preliminary group of 9 children, enhanced lysine levels support the suspicion of the existence of cystinuria without clinical symptoms. This also forms the basis for further necessary family histories as well as for prophylactic measures.

• Authors: W Berg, W Pirlich, O Kilian
• Journal: European urology (Eur Urol) Vol. 14 Issue 6 Pg. 458-63 ( 1988) ISSN: 0302-2838 [Print] Switzerland
• PMID: 3141195 (Publication Type: Journal Article)

Chemical References

• Indicators and Reagents
• Creatinine
• Lysine

Topics

• Child, Preschool
• Colorimetry
• Creatinine (urine)
• Cystinuria (genetics, prevention & control)
• Humans
• Indicators and Reagents
• Infant
• Lysine (urine)
• Mass Screening (methods)