Cellobiose/mannitol sugar absorption test in patients with dermatitis herpetiformis: a preliminary report.

Abstract

An abnormal cellobiose/mannitol ratio is present in new patients presenting with dermatitis herpetiformis and in patients who have never adhered to a strict gluten-free diet. In patients with dermatitis herpetiformis in remission on a strict gluten-free diet, small bowel absorption as measured by the cellobiose/mannitol ratio is normal. It is suggested that cellobiose/mannitol ratio absorption is a useful screening test for the intestinal abnormality associated with dermatitis herpetiformis and failure of the test to return to normal could suggest poor dietary compliance.

• Authors: J G Bridges, T J Robinson, K W Scott, H N Pearson
• Journal: The Ulster medical journal (Ulster Med J) Vol. 57 Issue 1 Pg. 45-9 (Apr 1988) ISSN: 0041-6193 [Print] Northern Ireland
• PMID: 3138803 (Publication Type: Journal Article)

Chemical References

• Disaccharides
• Cellobiose
• Mannitol

Topics

• Adult
• Aged
• Atrophy (etiology)
• Biopsy
• Cellobiose (pharmacokinetics)
• Dermatitis Herpetiformis (diet therapy, metabolism)
• Disaccharides (pharmacokinetics)
• Female
• Humans
• Intestinal Absorption
• Jejunum (pathology)
• Male
• Mannitol (pharmacokinetics)
• Middle Aged