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A case of pseudohypoparathyroidism type 1 associated with gonadotropin resistance and hypercalcitoninaemia.

Abstract
A case of a thirty-eight year old man with pseudohypoparathyroidism (PHP) type 1 associated with gonadotropin resistance and hypercalcitoninaemia was reported. The basal levels of the luteinizing hormone and follicle-stimulating hormone were elevated, and the responses to the luteinizing hormone-releasing hormone were exaggerated. The basal level of testosterone was normal, but the response to human chorionic gonadotropin was blunted. The serum calcitonin level was high, and hyper-responsiveness was observed by pentagastrin administration. From these results, it was suggested that partial testicular resistance to gonadotropin and the possibility of resistance to calcitonin were present in our case.
AuthorsY Kageyama, J Kawamura, A Ajisawa, T Yamada, K Iikuni
JournalJapanese journal of medicine (Jpn J Med) Vol. 27 Issue 2 Pg. 207-10 (May 1988) ISSN: 0021-5120 [Print] Japan
PMID3138479 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Chorionic Gonadotropin
  • Hormones
  • Parathyroid Hormone
  • Gonadotropin-Releasing Hormone
  • Luteinizing Hormone
  • Follicle Stimulating Hormone
  • Calcitonin
  • Pentagastrin
Topics
  • Adult
  • Calcitonin (blood)
  • Chorionic Gonadotropin
  • Follicle Stimulating Hormone (blood)
  • Gonadotropin-Releasing Hormone
  • Hormones (blood)
  • Humans
  • Luteinizing Hormone (blood)
  • Male
  • Parathyroid Hormone (blood)
  • Pentagastrin
  • Pseudohypoparathyroidism (blood, diagnosis)

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