Abstract |
Iliac crest biopsies and serum specimens were obtained from 36 non-dialyzed uraemic patients. The mean serum 25-hydroxycalciferol concentration of the patients was lower than that of normal subjects and a significant correlation was found between 25-hydroxycalciferol values and the severity of osteomalacia. Parathyroid osteopathy was significantly correlated with serum immunoreactive parathyroid hormone but not with serum 25-hydroxycalciferol values. While normal serum 25-hydroxycalciferol concentrations in uraemic patients do not exclude the presence of osteomalacia, a low concentration is virtually diagnostic of this disorder.
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Authors | R S Mason, D Moddel, A McElduff, J H Stewart, J F Mahony, S Posen |
Journal | Australian and New Zealand journal of medicine
(Aust N Z J Med)
Vol. 9
Issue 3
Pg. 257-60
(Jun 1979)
ISSN: 0004-8291 [Print] Australia |
PMID | 313783
(Publication Type: Journal Article)
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Chemical References |
- Antigens
- Ergocalciferols
- Parathyroid Hormone
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Topics |
- Antigens
- Ergocalciferols
(analogs & derivatives, blood)
- Humans
- Kidney Failure, Chronic
(blood, complications)
- Osteomalacia
(blood, complications, diagnosis)
- Parathyroid Hormone
(blood)
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