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Management of gonococcal ophthalmia neonatorum with single-dose kanamycin and ocular irrigation with saline.

Abstract
Two hundred nineteen neonates with gonococcal ophthalmia neonatorum, including 40 infected with penicillinase-producing strains, were treated as outpatients with a single intramuscular injection of 100 mg of kanamycin and hourly ocular irrigation with saline. Neisseria gonorrhoeae was isolated from three (1.4%) of the 212 babies attending for follow-up, and post-gonococcal conjunctivitis developed in 22 (10.4%) of those who returned for follow-up.
AuthorsA Latif, P Mason, E Marowa, E Paraiwa, F Dhamu, J Tambo, L Gwanzura, D Mapeta, G Jongeling
JournalSexually transmitted diseases (Sex Transm Dis) 1988 Apr-Jun Vol. 15 Issue 2 Pg. 108-9 ISSN: 0148-5717 [Print] United States
PMID3135607 (Publication Type: Journal Article)
Chemical References
  • Saline Solution, Hypertonic
  • Sodium Chloride
  • Kanamycin
Topics
  • Ambulatory Care
  • Female
  • Gonorrhea (drug therapy, microbiology)
  • Humans
  • Infant, Newborn
  • Kanamycin (administration & dosage, therapeutic use)
  • Male
  • Neisseria gonorrhoeae (isolation & purification)
  • Ophthalmia Neonatorum (drug therapy, microbiology)
  • Saline Solution, Hypertonic (administration & dosage)
  • Sodium Chloride (administration & dosage)
  • Therapeutic Irrigation

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