Changes in acute blood purification therapy in critical care: republication of the article published in the Japanese Journal of Artificial Organs.

Abstract

Acute blood purification therapy is an essential artificial organ in critical care. In the review article, looking back on the history, we describe our present knowledge and techniques of acute blood purification therapy in critical care. The topics include continuous hemodiafiltration (CHDF), online HDF as an artificial liver support, blood purification therapy aiming to remove pathogenic substances of sepsis, a procedure for connecting a CRRT device into an extra-corporeal membrane oxygenation circuit, and replacement fluid for CHDF. We also raise remaining issues and clarify the future direction of acute blood purification therapy in critical care. This review was created based on a translation of the Japanese review written in the Japanese Journal of Artificial Organs in 2017 (Vol. 46, No. 1, pp. 67-70), with adding some references.

• Authors: Taka-Aki Nakada, Shigeto Oda, Ryuzo Abe, Noriyuki Hattori
• Journal: Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs (J Artif Organs) Vol. 23 Issue 1 Pg. 14-18 (Mar 2020) ISSN: 1619-0904 [Electronic] Japan
• PMID: 31236729 (Publication Type: Journal Article, Review)

Topics

• Critical Care (methods)
• Extracorporeal Membrane Oxygenation (methods)
• Hemodiafiltration (methods)
• Humans
• Japan
• Sepsis (therapy)