Childhood haemorrhagic stroke: a 7-year single-centre experience.

Abstract

BACKGROUND:

In recent years, there has been increasing research interest in improving diagnostic and management protocols in childhood arterial ischaemic stroke (AIS). However, childhood stroke comprises, in approximately equal parts, both arterial ischaemic and haemorrhagic stroke (HS).

OBJECTIVE:

The aim of this study was to focus on the aetiology, clinical presentation, treatment and short-term outcome of children with spontaneous intracranial bleeding in a university hospital and elucidate differences to childhood AIS.

DESIGN:

We performed a retrospective analysis of electronic medical records of children (28 days-18 years) diagnosed with HS between 2010 and 2016.

RESULTS:

We included 25 children (male child, n=11) with a median age of 8 years 1 month. The most common clinical presentations were vomiting (48%), headache (40%) and altered level of consciousness (32%). In more than half of the patients, HS was caused by vascular malformations. Other risk factors were brain tumour, coagulopathy and miscellaneous severe underlying diseases. Aetiology remained unclear in one child. Therapy was neurosurgical in most children (68%). Two patients died, 5 patients needed further (rehabilitation) treatment and 18 children could be discharged home.

CONCLUSIONS:

HS differs from AIS in aetiology (vascular malformations as number one risk factor), number of risk factors ('mono-risk' disease), clinical presentation (vomiting, headache and altered level of consciousness) and (emergency) therapy.

• Authors: Lucia Gerstl, Katharina Badura, Florian Heinen, Raphael Weinberger, Aurelia Peraud, Franziska Dorn, Michaela V Bonfert, Steffen Berweck, Finbar J O'Callaghan
• Journal: Archives of disease in childhood (Arch Dis Child) Vol. 104 Issue 12 Pg. 1198-1202 (12 2019) ISSN: 1468-2044 [Electronic] England
• PMID: 31221624 (Publication Type: Journal Article)
• Copyright: © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Topics

• Adolescent
• Brain Ischemia (complications, diagnosis, physiopathology, therapy)
• Cerebrovascular Disorders (complications, diagnosis, physiopathology, therapy)
• Child
• Child, Preschool
• Electronic Health Records
• Female
• Humans
• Infant
• Intracranial Hemorrhages (diagnosis, etiology, physiopathology, therapy)
• Male
• Prognosis
• Retrospective Studies
• Risk Factors
• Stroke (diagnosis, etiology, physiopathology, therapy)