Elevated visceral fat area is associated with adverse postoperative outcome of radical colectomy for colon adenocarcinoma patients.

Abstract

OBJECTIVE:

To assess the impact of visceral obesity quantified by preoperative computed tomography on short-term postoperative outcomes compared with body mass index (BMI) in stage I-III colon adenocarcinoma patients.

METHODS:

In this retrospective study, 107 patients treated with radical colectomy for stage I-III colon adenocarcinoma were classified as obese or non-obese by computed tomography-based measures or BMI (obese: BMI ≥28 kg/m2 , visceral fat area (VFA) to subcutaneous fat area ratio (V/S) ≥0.4, and VFA ≥100 cm2 ). Clinical variables, operation time, estimated blood loss, pathologic stage, histologic grade, postoperative complications, postoperative stay and hospitalization expenses were compared.

RESULTS:

Obese patients by VFA were more likely to have higher postoperative complication rate (32.9 versus 11.8%, P = 0.021), have longer operation time (184.6 ± 49.5 versus 163.1 ± 44.1 min, P = 0.033), postoperative stay (15.21 ± 7.59 versus 12.29 ± 5.40 days, P = 0.047) and cost more ($10 758.7 ± 3271.7 versus $9232.0 ± 2994.6, P = 0.023) than non-obese.

CONCLUSION:

Visceral obesity graded by VFA is associated with increased postoperative morbidity, operation time, postoperative stay and hospitalization expenses for colon adenocarcinoma patients and may be superior to BMI or V/S for the prediction of colon surgery.

• Authors: Ting-Shuai Zhai, Yuan Kang, Wen-Hao Ren, Qi Liu, Chao Liu, Wei-Zheng Mao
• Journal: ANZ journal of surgery (ANZ J Surg) Vol. 89 Issue 9 Pg. E368-E372 (09 2019) ISSN: 1445-2197 [Electronic] Australia
• PMID: 31206986 (Publication Type: Comparative Study, Journal Article)
• Copyright: © 2019 Royal Australasian College of Surgeons.

Topics

• Adenocarcinoma (surgery)
• Aged
• Body Mass Index
• Colectomy (methods)
• Colonic Neoplasms (pathology, surgery)
• Female
• Health Care Costs
• Humans
• Laparoscopy
• Length of Stay (statistics & numerical data)
• Male
• Neoplasm Grading
• Neoplasm Staging
• Obesity, Abdominal (complications, diagnostic imaging)
• Operative Time
• Postoperative Complications
• Retrospective Studies
• Risk Factors
• Tomography, X-Ray Computed